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Europe Dental Bone Grafts and Substitutes Market Size Worth US$ 435.66 Million by 2030 | CAGR: 6.9%

According to the study undertaken by Astute Analytica, Europe dental bone grafts and substitutes market was valued at US$ 243.31 Million in 2021 and is forecasted to reach US$ 435.66 Million by 2030. The market is expected to register a CAGR of 6.9% during the forecast period 2022-2030.

Bone grafting has been one of the successful methods of implant surgery due to the development of its advanced substitutes and well-developed technological procedures. Regulatory restrictions regarding the use of allograft materials in Europe have led to a shift to the use of more synthetic grafting materials over allograft materials. Moreover, this surgery is typically performed prior to the insertion of dental implants or when nearby teeth are being badly affected by bone loss. Furthermore, France is expected to grow with the highest CAGR of 7.8%, followed by the UK as France is investing heavily in research and development in order to provide better care for patients.

Market Dynamics and Trends 


Factors such as the development of biocompatible synthetic bone grafts and an increase in demand for dental bone grafts boost the Europe dental bone grafts and substitutes market during the forecast period. A biomaterial's purpose is to aid in the regeneration of bone tissue at the defect location, then decay in situ and be replaced by freshly created bone tissue. The most prevalent application of bone grafting is in the placement of dental implants to repair a lost tooth's edentulous region. Due to developments in dental implantology and the growing demand for cranial bony defect repair, the use of bone grafts and substitutes in dentistry has expanded dramatically in recent years. 


Higher costs of surgeries and ethical issues related to bone grafting procedures is a restraining factor that inhibits the growth of the market during the forecast period. The type of material utilized, as well as the technique, have a significant impact on the cost of a bone graft. It is one of the most expensive therapies because many surgical operations are required. Also, it is extremely successful and safe as tissue is extracted from the patient's body. Moreover, patients may have ethical, religious, or medical concerns regarding the origins of bone grafts as the majority of refusals were motivated by fear of failure, discomfort, or illness.


Technological advancements in the medical field are the current trend in the market. SMART bone grafting is a cutting-edge bone grafting procedure that regenerates the jawbone with only one minor incision as a result, healing time is reduced. Moreover, recent advances in hydroxyapatite HA-based bone substitute materials have improved biomechanical capabilities. 

Market Insights

Europe Dental Bone Grafts and Substitutes Market Insights by Product

Based on product, the market is segmented into xenograft, autograft, allograft, and synthetic analysis. The autograft segment holds the largest share in the market in 2021 and is also anticipated to grow at the highest CAGR of 7.5% during the forecast period. Autogenous bone graft remains a reliable treatment option when structural stability is required, or bone voids exist. Moreover, synthetic bone grafting is the emerging alternative to autografts as it is biocompatible and made from proteins that are naturally found in our own bodies.

Europe Dental Bone Grafts and Substitutes Market Insights by Treatment Type 

Based on treatment, the market is segmented into natural bone grafts, synthetic bone graft substitutes, and others. The natural bone grafts segment held the largest market share in 2021. Whereas the synthetic bone graft substitutes segment is expected to grow at the highest CAGR of 7.5% during the forecast period. Calcium phosphate cement (CPC) is one of the most promising bone filling materials under synthetic bone grafts substitutes.

Europe Dental Bone Grafts and Substitutes Market Insights by Application

Based on application, the market is bifurcated into research & development and clinical applications. The clinical applications segment dominated the market in 2021 as the main application of bone grafting is in the clinical field. They are used in clinical trials, bone reconstruction, clinical research, tissue engineering, microbiology, etc. hence, anticipated to grow at the highest CAGR of 7.7% over the forecast period. Bone grafting is used in clinical trials, bone reconstruction, clinical research, tissue engineering, microbiology, etc.

Europe Dental Bone Grafts and Substitutes Market Insights by End User

Based on end-users, the market is segmented into biopharmaceutical companies, contract research organizations, contract manufacturing organizations, and academic & research institutes. The contract manufacturing organizations dominated the market in 2021 due to the increasing prevalence of periodontal disease and the presence of a wide number of dental clinics. It is also expected to register the highest CAGR of 7.8% during the forecast period. 

Epidemiology of Dental Problems (Bone Related) in Europe 

According to Economist Intelligence Unit (EIU)

  • In the UK, the prevalence of chronic periodontitis has remained at approximately 45%. The peak in incidence comes between the ages of 60 and 64, and there are significant socioeconomic disparities.
  • Periodontitis affects 69% of adults and 92% of seniors in Germany, according to a survey. Periodontal prevalence was significantly higher in male subjects and East German subjects.
  • Between the ages of 35 and 64, 47% of French patients have severe periodontal pocket depth exceeding 4 mm.
  • According to research, the prevalence estimates of severe and moderate periodontitis are 34.94% and 40.78% respectively in Italy. In Italy, children as young as three years old have a significant prevalence of tooth decay. Children accounted for 56% of all decaying teeth.

Company Profile 

  • Ivoclar Vivadent AG is a dental company that manufactures a variety of products & systems for dentists and dental professionals all over the world. Digital dentistry, direct restoratives, fixed prosthetics, and removable prosthetics are the four product areas in which Ivoclar Vivadent operates. 
  • Zimmer Biomet is a medical devices company that provides support through focused corporate giving, including financial, volunteer, and in-kind support for non-profit organizations, charitable surgeries, and professional medical education. Moreover, the company offers medical devices for knees, hips, and trauma. Zimmer Biomet offers a comprehensive portfolio of hip products that combine rich clinical heritage with modern technological advancements.
  • Dentsply Sirona Inc. is a global dental product and technology company that designs, develops, manufactures, distributes, and sells a variety of dental products and technologies. Treatment facilities, imaging equipment, motorized dental handpieces, and other devices are among the items available. The company provides dental CAD/CAM products, digital impressions intraoral scanners, mills, and services; and orthodontic products, including high-frequency vibration technology devices.

Competitive Landscape

The key players in the Europe dental bone grafts and substitutes market are Ivoclar Vivadent, Zimmer Biomet, Dentsply Sirona, Nobel Biocare, Medtronic, BioHorizons IPH, Inc., ACE Surgical Supply Company, Geisclich Pharma AG and Straumann Group among others. Through extensive research, it is found that big players have adopted various competitive strategies such as mergers & acquisitions in order to have a grip on an emerging market. Furthermore, leading companies are expanding their geographical boundaries by acquiring small brands and domestic companies.

Segmentation Overview 

Europe dental bone grafts and substitutes market is segmented based on product, treatment type, application, end-user, and region. The industry trends in the market are sub-divided into different categories in order to get a holistic view of the Europe marketplace.

Following are the different segments of the Europe Dental Bone Grafts and Substitutes Market:

By Product segment 

  • Xenograft
  • Autograft
  • Allograft
  • Synthetic Analysis

By Treatment Type segment 

  • Natural bone grafts
    • Autologous bone grafts
    • Cancellous autografts
    • Cortical autografts
    • Allogeneic bone grafts
    • Cancellous allografts
    • Demineralized bone matrix (DBM)
  • Synthetic bone graft substitutes
    • Calcium sulphate
    • Calcium phosphate ceramics (CaP ceramics)
    • Tricalcium phosphate (TCP)
    • Biphasic calcium phosphate (BCP)
    • Calcium phosphate cements (CPC)
    • Others
  • Others

By Application segment 

  • Research & Development
  • Clinical Applications

By End User segment 

  • Biopharmaceutical Companies
  • Contract Research Organizations
  • Contract Manufacturing Organizations
  • Academic & Research Institutes

By Country segment 

  • The UK
  • Germany
  • France
  • Italy
  • Spain
  • Netherland
  • Turkey
  • Rest of Europe 

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