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Japan Epigenetics Market Size Worth US$ 48.6 Million by 2027 |CAGR: 12.8%

According to the study undertaken by Astute Analytica, the Japan epigenetics market held a market value of US$ 23.6 Million in 2021 and is estimated to reach US$ 48.6 Million by the year 2027. The market is expected to register a CAGR of 12.8% during the forecast period 2022-2027. 

Epigenetics is a branch of genetics concerned with the study of cellular and physiological trait variations caused by environmental or ecological factors that turn genes on and off and influence cellular ability to read genes without being affected by genotype changes. Epigenetics causes changes in an organism's phenotype rather than genotype, with the underlying DNA or RNA sequence remaining constant. Moreover, epigenetic changes are essential for development since they are dynamic and change in response to external stimuli. These modifications, on the other hand, can be stable and passed down from generation to generation. Biology and genetic expressions of most organisms are affected by epigenetics, which makes it one of the most crucial fields of developmental genetics and molecular biology. Also, epigenetic dysregulation is generally related to human disease, especially cancer. 

However, the novel COVID-19 has seen a significant impact on the epigenetics market. Japan epigenetics market is witnessed a slight decline of approx. 3.2% in 2020, in the recent outbreak of the COVID-19 pandemic.

Market Dynamics and Trends 


Factors such as growing R&D expenditure in the pharmaceutical & biopharmaceutical industry and growing adoption of epigenetics for cancer treatmentwill boost the Japan epigenetics market during the forecast period. The growth in investments and spending on pharmaceutical research and development (R&D) coupled with the increasing pressure on healthcare providers to reduce healthcare cost is expected to propel the market growth. Growing commercial success of biopharma companies across developed and developing economies led to new biological drugs which is further boosting the biologics manufacturing services in the Japan epigenetics market during the forecast period. Moreover, the increasing adoption of epigenetics for cancer treatment drive the demand for epigenetics as these drugs may make cancer cells more sensitive to these therapies, making them work better and more likely to prevent cancer from coming back. Also, the rise in n umber of cancer patients will drive the demand for epigenetics thereby boosting the market growth.


High costs of epigenetics instruments and dearth of skilled workforce is a restraining factor which inhibits the growth of the market during the forecast period. Instruments and machines required for epigenetics research are expensive as they are equipped with advanced technologies for analysis and functionalities. Also, the proliferation of technological advancements in the market has increased the demand for skilled professionals for the management of systems and analysis. However, the shortage of staff in lucrative areas, has led to unpredictable uncertainties in the epigenetics market growth. 


Innovative growth strategies are likely to provides a lucrative growth trend in the Japan epigenetics market. The rapid growth of epigenetics in the Japan, has insisted companies to take innovative marketing and positioning strategies which are likely to provide innovative products through launches and partnerships. Moreover, the market players operating in the market have largely adopted groundbreaking marketing strategies in order to gain a competitive advantage in the marketplace. 

Market Insights 

Japan Epigenetics Market Insights by Product Type

Based on product type, the epigenetics market is segmented into reagents, kits, instruments, software tools, enzymes, proteins & peptides, antibodies and services. The kits segment is further segmented into bisulfite conversion kits, chip kits, RNA kit and others. The software tools are segmented into EpiGRAPH, BiQ analyzer, RnBeads and others. The kits segment holds the largest share in the Japan epigenetics market in 2021 and is also anticipated to hold the highest CAGR. Due to its high application from research activities and their sheer usage, need throughout the protocol and other pre-requisite steps of DNA analysis have led to the segmental growth. 

Japan Epigenetics Market Insights by Technology

Based on technology, the epigenetics market is segmented into DNA methylation, histone methylation, histone acetylation, bromodomains, non-coding RNA and others. The DNA methylation segment is anticipated to hold the largest market share over the forecast period owing to the high usage of this technique in the research and academic institutes. Moreover, bromodomains segment is projected to hold the highest CAGR over the forecast period. 

Japan Epigenetics Market Insights by Application

Based on application, the epigenetics market is segmented into oncology and non-oncology. The non-oncology segment is further bifurcated into cardiovascular diseases, neurodegenerative and autoimmune. The oncology segment dominated the Japan epigenetics market in 2021 and is also anticipated to grow at the highest CAGR over the forecast period. Increase in the adoption of epigenetics for oncology, higher number of R&D activities and availability of wide variety of products majorly fuel the market growth. 

Japan Epigenetics Market Insights by End-Users

Based on end-users, the epigenetics market is segmented into academic and research institutes, pharmaceutical & biotechnology companies, contract research organizations (CROs) and research and consulting firms. The pharmaceutical & biotechnology companies held the highest share in the Japan epigenetics market in 2021. Increase in R&D activities and growing demand for drug discovery due to rise in geriatric population along with surging incidence of chronic disease is fostering the market growth. Moreover, the academic and research institutes segment is expected to project the highest CAGR during the forecast period. 

Government initiatives for research activities in the epigenetics

The Japan Agency for Medical Research and Development (AMED) and the Canadian Institutes of Health Research (CIHR) continue their long-standing collaboration with the recently announced results of the funding opportunity to support the advancements in epigenetic technologies. This collaboration will bring funding opportunity which supports international collaborative research projects for the advancement of high impact epigenetic research between early career researchers in Canada and Japan. Also, the increasing government investments towards cancer care have further fostered the growth of the market. The exponential rise in healthcare spending and technological advancements in the country drives the growth of the epigenetics market.

Competitive Insight

Japan Epigenetics Market is highly competitive in order to increase their presence in the marketplace. Some of the key players operating in the Japan epigenetics market include Epigenereon, National Institute of Genetics, Rhelixa Inc., RIKEN, Illumina, Inc., Daiichi Sankyo Company Limited, Takeda Pharmaceutical Company Limited and Abcam PLC among others.

Segmentation Overview 

Japan Epigenetics Market is segmented based on product type, technology, application, end-users and country. The industry trends in the epigenetics market are sub-divided into different categories in order to get a holistic view of the Japan marketplace. 

Following are the different segments of the Japan Epigenetics Market:

By Product Type segment of the Japan Epigenetics Market is sub-segmented into:

  • Reagents
  • Kits
    • Bisulfite Conversion Kits
    • ChIP Kits
    • RNA Kit
    • Others
  • Instruments 
  • Software Tools
    • EpiGRAPH
    • BiQ Analyzer
    • RnBeads
    • Others
  • Enzymes
  • Proteins & Peptides
  • Antibodies
  • Services

By Technology segment of the Japan Epigenetics Market is sub-segmented into:

  • DNA Methylation
  • Histone Methylation
  • Histone Acetylation
  • Bromodomains
  • Non-coding RNA
  • Other

By Application segment of the Japan Epigenetics Market is sub-segmented into:

  • Oncology
  • Non-oncology
    • Cardiovascular diseases
    • Neurodegenerative
    • Autoimmune

By End-Users segment of the Japan Epigenetics Market is sub-segmented into:

  • Academic and Research Institutes
  • Pharmaceutical & Biotechnology Companies
  • Contract Research Organizations (CROs)
  • Research and consulting firms

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